Depression and Anxiety Predict Health-Related Quality of Life
in Chronic Obstructive Pulmonary DiseaseBlakemore A, Dickens C, Guthrie E, et alInt J Chron Obstruct Pulmon Dis. 2014;9:501-512.
Chronic obstructive pulmonary disease COPD has long been known to have several comorbidities, but psychiatric disorders have not figured prominently among them. A recent meta-analysis looks at 2 measures of psychiatric health in relation to health-related quality of life HRQoL in patients with COPD. Patients with spirometry-confirmed COPD and in whom a validated HRQoL including measures of depression and anxiety had been performed were included. The studies were longitudinal in order to determine whether depression and anxiety predicted the risk for subsequent HRQoL in COPD patients. Six studies encompassing 895 COPD patients formed the basis of the study. The authors found a strong positive correlation between tests for depression and subsequent impairment of HRQoL r = 0.48, P < .001. Similarly, they found a correlation between tests for anxiety and respiratory-specific HRQoL r = 0.36, P < .001.