Physical activity decreases substantially over time in patients with chronic obstructive pulmonary disease (COPD) at all levels of severity, according to a new study from researchers in Germany. This decline in physical activity is accompanied by a worsening of lung function and health status, and sustained physical inactivity is associated with progression of both exercise intolerance and muscle depletion.”
Physical inactivity is associated with morbidity and mortality in COPD, but the association between objectively measured physical activity and other disease components over time has not been well studied,” said lead author Benjamin Waschki, MD, of the Pulmonary Research Institute at LungenClinic in Grosshansdorf, Germany. “
In our prospective cohort study, we evaluated the longitudinal association between changes in physical activity and disease progression in 137 patients with COPD and 26 patients with chronic bronchitis.”
The findings were published online ahead of print publication in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.