Monthly Archives: September 2016


The disease burden of chronic obstructive pulmonary disease in Greece

This survey provides insightful data regarding the impact of COPD on Greek patients’ everyday life, psychology, and productivity, revealing the increased individual morbidity and the significant burden of this condition on society. International Journal of Chronic Obstructive Pulmonary Disease, 2016 Volume 2016:11(1) Pages 2179—2189 Authors Kourlaba G, Hillas G, Vassilakopoulos T, […]


Triple-combination therapy reduces COPD exacerbations

GlaxoSmithKline and Innoviva’s triple-combination therapy of fluticasone furoate, umeclidinium and vilanterol significantly reduced the amount of exacerbations experienced by patients with chronic obstructive pulmonary disease compared with AstraZeneca’s Symbicort Turbohaler, according to phase 3 study results presented at the 2016 European Respiratory Society International Congress. Results showed that patients in […]


Effectiveness of Fluticasone Furoate–Vilanterol for COPD in Clinical Practice

Guidelines on the management of chronic obstructive pulmonary disease (COPD) are based on numerous randomized, controlled trials of efficacy, which are usually generated for registration purposes. However, these trials have included patients who were selected with the use of strict criteria and were closely monitored, and therefore the results have […]


Pulmonary rehabilitation as a mechanism to reduce hospitalizations for acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis

Abstract Background  Acute exacerbations of COPD (AECOPD) have a significant impact on healthcare utilization, including physician visits and hospitalizations. Previous studies and reviews have shown that pulmonary rehabilitation has many benefits but the effect on hospitalizations for AECOPD is inconclusive. Methods  A literature search was carried out to find studies […]


Do self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis

Self-management interventions exert positive effects in patients with COPD on respiratory-related and all-cause hospitalizations and modest effects on 12-month health-related quality of life, supporting the implementation of self-management strategies in clinical practice. Benefits seem similar across the subgroups studied and limiting self-management interventions to specific patient subgroups cannot be recommended. Authors […]